drawing the line- is Harlem really too far north?

Where do you draw the line? I'm talking about on the island of Manhattan.  I remember when I was nervous about going north of 110th- everyone told me about how sketchy it was. But we visited friends there and couldn't figure out what the deal was.

So know what? I am not sure they're right.

We're apartment hunting looking specifically above 100th. And we've gotten some concerned talks from family...but what do they know about an area they haven't been to in 25 or so years.

Any how, if you live above 110th and love your neighborhood, give it a shout out in the comments...